al-Arfaj H F, Naddaf H O
Department of Medicine, King Khalid University Hospital, King Saud University, Kingdom of Saudi Arabia.
Lupus. 1995 Oct;4(5):412-4. doi: 10.1177/096120339500400513.
Central nervous system involvement in systemic lupus erythematosus (SLE) is common; this is especially so in patients with positive antiphospholipid antibody. However, cerebellar involvement is very unusual. In our institution, we have seen 150 cases of SLE over the last 10 years; however, this is the only patient who has cerebellar involvement due to SLE. The patient had no other neurological deficit, and no other cause apart from her SLE to explain her cerebellar ataxia. Her antiphospholipid antibody was negative. The patient showed some improvement on high-dose steroids and azathioprin.
系统性红斑狼疮（SLE）累及中枢神经系统很常见；抗磷脂抗体阳性的患者尤其如此。然而，小脑受累非常罕见。在我们机构，过去10年里共诊治了150例SLE患者；但这是唯一因SLE出现小脑受累的患者。该患者无其他神经功能缺损，除SLE外没有其他原因可解释其小脑共济失调。她的抗磷脂抗体为阴性。该患者在大剂量使用类固醇和硫唑嘌呤后病情有所改善。
