Molochkina E M, Dzhaman U M, Ozerova I B, Burlakova E B, Shishkina L N
Radiats Biol Radioecol. 1995 Nov-Dec;35(6):860-8.
Some characteristics of mice brain nerve-endings' lipid phase were studied (total lipids, total and individual phospholipids and cholesterol contents, their ratios, lipid peroxidation level, rigidity index) after single low dose, whole body gamma-irradiation (15 cGy) with dose intensities of 0.01, 0.25, 9.0 cGy/min. Some markedly expressed alterations were found out in those parameters. Brain membranes functioning also changed significantly as it was judged by membrane-bound acetylcholinesterase activity. All the changes revealed complicated dependence both on dose intensity and on time period after irradiation. The ranges of the observed changes suppose CNS state to have been modified by low dose irradiation including CNS sensibility to external psycho- and neurotrophic factors.
研究了单次低剂量全身γ射线照射（15 cGy），剂量率分别为0.01、0.25、9.0 cGy/min后小鼠脑神经末梢脂质相的一些特征（总脂质、总磷脂和各磷脂及胆固醇含量、它们的比例、脂质过氧化水平、刚性指数）。在这些参数中发现了一些明显的变化。从膜结合乙酰胆碱酯酶活性判断，脑膜功能也发生了显著变化。所有这些变化显示出对剂量率和照射后时间段的复杂依赖性。观察到的变化范围表明，低剂量照射改变了中枢神经系统的状态，包括中枢神经系统对外界心理和神经营养因子的敏感性。
