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[切尔诺贝利原子能发电站周边30公里区域内根田鼠(Microtus oeconomus)大脑的生化变化]

[Biochemical changes in the brain of the root vole (Microtus oeconomus) from a 30-kilometer zone around the Chernobyl Atomic Electric Power Station].

作者信息

Kudiasheva A G, Zagorskaia N G, Shevchenko O G

出版信息

Ukr Biokhim Zh (1978). 1996 Mar-Apr;68(2):87-93.

PMID:9005669
Abstract

Deviations in lipid peroxidation parameters and in activity of dehydration enzymes in the brain of the tundra voles inhabiting areas with higher level of technogenic contamination (the 30-km zone of the Chernobyl NPP and the Republic of Komi) have been analyzed. During the first years after the disaster a decrease in the lipid antioxidative status of the brain and dehydrogenase activity, changes in the lipid composition of voles trapped in the disaster zone in comparison with control ones were more significant. Relative stabilization of the phospholipid composition with low antioxidizing activity of lipids and slight activity of succinate and piruvate dehydrogenases has been observed in a distant period of analysis.

摘要

对生活在技术污染水平较高地区(切尔诺贝利核电站30公里区域和科米共和国)的苔原田鼠大脑中脂质过氧化参数和脱水酶活性的偏差进行了分析。在灾难后的头几年,与对照组相比,受灾地区捕获的田鼠大脑脂质抗氧化状态和脱氢酶活性下降,脂质组成发生变化,这些变化更为显著。在分析的后期,观察到磷脂组成相对稳定,脂质抗氧化活性较低,琥珀酸和丙酮酸脱氢酶活性轻微。

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