Taylor T W, Yamaguchi T
Department of Bio-Medical Engineering, School of High-Technology for Human Welfare, Tokai University, Japan.
Med Eng Phys. 1995 Dec;17(8):602-8. doi: 10.1016/1350-4533(95)00017-h.
A realistic model of the left ventricle of the human heart was constructed using a cast from a dog heart which was in diastole. A coordinate measuring machine was used to measure and digitize the coordinates of the left ventricle. From the complex measured left ventricle shape values, a three-dimensional finite volume representation was constructed using a simulation package. The left ventricular walls moved towards the centre of the aortic outlet in order to study the effects of time-varying left ventricular ejection. The left ventricular wall motion was assumed to follow the blood flow and the wall grid was reformed 25 times during the calculation. The 25.8 cm3 ventricular volume was reduced by 75% in 0.25 s. Centreline and cross-sectional velocity vectors greatly increased in magnitude at the aortic outlet, and most of the pressure occurred in the top 15% of the heart. The computational method should make it possible to compare simulation results with important measurement techniques such as ultrasound and magnetic resonance imaging, and this should allow a finer detail of flow understanding than is presently available using either a modelling or imaging method alone.
利用处于舒张期的狗心脏铸型构建了一个真实的人类心脏左心室模型。使用坐标测量机测量左心室的坐标并将其数字化。根据测得的复杂左心室形状值，使用模拟软件包构建了三维有限体积表示。左心室壁朝着主动脉出口中心移动，以研究时变左心室射血的影响。假设左心室壁运动遵循血流情况，并且在计算过程中壁网格重新划分了25次。25.8立方厘米的心室容积在0.25秒内减少了75%。主动脉出口处的中心线和横截面速度矢量大小大幅增加，并且大部分压力出现在心脏顶部的15%区域。该计算方法应能使模拟结果与诸如超声和磁共振成像等重要测量技术进行比较，并且这应能比目前单独使用建模或成像方法更详细地了解血流情况。
