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严重精神疾病患者的生活质量及再住院的临床预测因素

Quality of life and clinical predictors of rehospitalization of persons with severe mental illness.

作者信息

Postrado L T, Lehman A F

机构信息

Department of Psychiatry, University of Maryland, Baltimore 21201, USA.

出版信息

Psychiatr Serv. 1995 Nov;46(11):1161-5. doi: 10.1176/ps.46.11.1161.

Abstract

OBJECTIVE

The study examined whether rehospitalization of patients with severe and persistent mental illness could be predicted by patients' quality of life. The predictive ability of two clinical factors associated with rehospitalization--history of hospitalizations and severity of symptoms--was also examined.

METHODS

A total of 559 patients were assessed at two follow-up points, two and 12 months after an index hospital discharge. Patients who were rehospitalized and those who were not rehospitalized between the two follow-up points were compared on subjective and objective quality of life, symptom severity at first follow-up, and previous rehospitalization. Multivariate analysis was used to determine the best predictors of rehospitalization.

RESULTS

Compared with patients who were not rehospitalized, those who were rehospitalized had more severe symptoms and were more likely to have a history of hospitalization. Rehospitalized patients reported more dissatisfaction with family relations and were more likely to report an arrest in the past two months. The two groups did not differ in other quality-of-life domains and in global quality of life.

CONCLUSIONS

The best predictors of rehospitalization were previous rehospitalization, more severe symptoms, and dissatisfaction with family relations. Interventions should promote positive relationships between patients with severe mental illness and their families to reduce the risk of relapse and rehospitalization.

摘要

目的

本研究探讨严重持续性精神疾病患者的再住院情况能否通过患者的生活质量进行预测。同时还研究了与再住院相关的两个临床因素——住院史和症状严重程度——的预测能力。

方法

共有559名患者在出院后的两个随访点(出院后2个月和12个月)接受评估。对在两个随访点之间再次住院的患者和未再次住院的患者在主观和客观生活质量、首次随访时的症状严重程度以及既往住院史方面进行比较。采用多变量分析来确定再住院的最佳预测因素。

结果

与未再次住院的患者相比,再次住院的患者症状更严重,且更有可能有住院史。再次住院的患者对家庭关系的满意度更低,且更有可能报告在过去两个月内曾被捕。两组在其他生活质量领域和总体生活质量方面没有差异。

结论

再住院的最佳预测因素是既往住院史、更严重的症状以及对家庭关系的不满。干预措施应促进严重精神疾病患者与其家人之间的积极关系,以降低复发和再住院的风险。

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