Wu B, Gao L, Han T
Department of Cardiology, 2nd Affiliated Hospital of Suzhou Medical College, Jiangsu.
Zhonghua Nei Ke Za Zhi. 1995 May;34(5):295-7.
Heart rate power spectral analysis in 44 patients with coronary artery disease was obtained from 24-hour dynamic electrocardiogram. 195 episodes of transient myocardial ischemia that was defined as horizontal or down sloping depression of the ST segment of > or = 0.1 mV and lasted for > or = 2 minutes were studied. The area of low frequency components (LF, 0.02-0.10 Hz) representing predominontly sympathetic tone with some contribution from the parasympathetic tone and that of high frequency components (HF, 0.15-0.40 Hz) representing mainly parasympathetic tone and the value of LF/HF on 4 minute heart rate power spectral graph at the deepest depression of ST segment were compared with that before the episode of myocardial ischemia. The area of HF of fast rate myocardial ischemia occurring in night reduces significantly (P < 0.001), the value of LF/HF increases markedly (P < 0.05) and the area of LF increases slightly. The results suggest that there is a change of autonomic nervous activity during the episode of fast rate myocardial ischemia in night, parasympathetic nervous tone decreases markedly, there may be secondary increase of sympathetic nervous activity.
对44例冠心病患者进行24小时动态心电图检查,获取心率功率谱分析结果。研究了195次短暂性心肌缺血发作,其定义为ST段水平或下斜型压低≥0.1 mV且持续≥2分钟。比较了ST段最深压低时4分钟心率功率谱图上代表主要交感神经张力且有部分副交感神经张力贡献的低频成分(LF,0.02 - 0.10 Hz)面积、代表主要副交感神经张力的高频成分(HF,0.15 - 0.40 Hz)面积以及LF/HF值与心肌缺血发作前的情况。夜间发生的快速心率心肌缺血的HF面积显著减小(P < 0.001),LF/HF值显著升高(P < 0.05),LF面积略有增加。结果表明,夜间快速心率心肌缺血发作期间自主神经活动发生改变,副交感神经张力显著降低,交感神经活动可能继发增加。