Hendrix D V, Brooks D E, Smith P J, Gelatt K N, Miller T R, Whittaker C, Pellicane C, Chmielewski N
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0126, USA.
Equine Vet J. 1995 Nov;27(6):440-7. doi: 10.1111/j.2042-3306.1995.tb04425.x.
The medical records of 24 horses with corneal stromal abscesses were reviewed. Twenty of the horses initially presented with a corneal ulcer, corneal opacity, or evidence of ocular pain. All of the horses were treated with topical antibiotics prior to referral. Most had also been treated with topical atropine sulphate and systemic flunixin meglumine. Ophthalmic examinations revealed focal, yellow-white corneal opacities, corneal vascularisation and evidence of iridocyclitis. Nine of the horses were treated primarily medically as the initial response to topical and systemic medication was rapid. Fifteen horses were treated both medically and surgically. Surgical treatment was undertaken when corneal rupture was imminent, the iridocyclitis was intractable or when there was minimal response to intensive medical therapy. The surgical procedure performed in most cases was a deep keratectomy with a conjunctival pedicle flap. Intraoperative specimens for cytology, culture, and/or histopathology contributed to the aetiological diagnosis in 5 of 8 cases in which preoperative cytology and cultures were nondiagnostic. All horses, excluding one that was enucleated at presentation for iris prolapse, had vision at discharge.
回顾了24匹患有角膜基质脓肿马匹的病历。其中20匹马最初表现为角膜溃疡、角膜混浊或眼痛症状。所有马匹在转诊前均接受了局部抗生素治疗。大多数马匹还接受了局部硫酸阿托品和全身性氟尼辛葡甲胺治疗。眼科检查发现有局灶性黄白色角膜混浊、角膜血管化及虹膜睫状体炎迹象。9匹马主要接受药物治疗，因为局部和全身用药的初始反应迅速。15匹马接受了药物和手术联合治疗。当角膜即将破裂、虹膜睫状体炎难以控制或强化药物治疗反应甚微时，便会进行手术治疗。大多数病例实施的手术是带结膜蒂瓣的深层角膜切除术。在术前细胞学检查和培养无诊断结果的8例病例中，有5例术中采集的细胞学、培养及/或组织病理学标本有助于病因诊断。除1例因虹膜脱出在就诊时被摘除眼球的马匹外，所有马匹出院时均有视力。
