Wassilew S W, Rohde B T, Jänner M
Dermatologica. 1977;154(3):168-76.
A short summary of normolipemic xanthomatoses is exposed. A case of xanthoma disseminatum is reported. The typical clinical picture is described and numerous investigations are recorded. No association with any systemic disorder neither diabetes insipidus nor rheumatoid arthritis could be found. Histologically the granulomas consist of many multinuclear giant cells embedded in an infiltration of histiocytic cells and lymphocytes. Fat staining demonstrates lipid accumulation as a secondary phenomenon. Systemic corticosteroid therapy was effective in preventing the regrowth of the granulomas after their surgical removal.
本文简要介绍了血脂正常性黄瘤病。报告了一例播散性黄瘤病例。描述了典型的临床表现并记录了大量检查结果。未发现与任何全身性疾病有关，既无尿崩症也无类风湿性关节炎。组织学上，肉芽肿由许多多核巨细胞组成，这些巨细胞嵌入组织细胞和淋巴细胞浸润中。脂肪染色显示脂质积聚是一种继发性现象。全身皮质类固醇治疗在手术切除肉芽肿后可有效防止其再生。
