Yamanaka K, Ogura T, Niki H, Hiraga S
Department of Molecular Cell Biology, Kumamoto University School of Medicine, Japan.
FEMS Microbiol Lett. 1995 Nov 1;133(1-2):59-63. doi: 10.1111/j.1574-6968.1995.tb07861.x.
The mukB operon is located at 21 min on the Escherichia coli chromosome and seems to consist of four genes, orf30 (smtA), mukF, mukE, and mukB. Based on sequence similarity, the promoter-proximal gene, orf30 (smtA), could encode an S-adenosylmethionine-dependent methyltransferase. The smtA gene is not essential for cell growth and its expression is positively regulated by H-NS, an Escherichia coli histone-like protein.
mukB操纵子位于大肠杆菌染色体上21分钟处，似乎由四个基因组成，即orf30（smtA）、mukF、mukE和mukB。基于序列相似性，启动子近端基因orf30（smtA）可能编码一种依赖S-腺苷甲硫氨酸的甲基转移酶。smtA基因对于细胞生长并非必需，其表达受到大肠杆菌类组蛋白H-NS的正调控。
