膜性结肠炎中结肠黏膜的氨基葡萄糖合成酶活性
Glucosamine synthetase activity of the colonic mucosa in membranous colitis.
作者信息
Goodman M J, Kent P W, Truelove S C
出版信息
Gut. 1977 Mar;18(3):229-31. doi: 10.1136/gut.18.3.229.
Abstract
Glucosamine synthetase, the first enzyme in glycoprotein synthesis, has been measured in serial rectal biopsies in four patients with membranous colitis. In two of the patients the levels of the enzyme were very high initially and in the other two patients the enzyme levels rose to a peak above the normal range after a delay of up to 10 days. These high levels may be related to the mucus hypersecretion which is a feature of membranous colitis but it seems more likely that they represent the healing of the mucosa.
摘要
葡糖胺合成酶是糖蛋白合成中的首个酶，已在4例膜性结肠炎患者的系列直肠活检中进行了检测。其中2例患者最初该酶水平非常高，另外2例患者的酶水平在延迟长达10天后升至高于正常范围的峰值。这些高水平可能与膜性结肠炎的特征性黏液分泌过多有关，但似乎更有可能代表黏膜的愈合。
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本文引用的文献
1
Pseudo-membranous colitis.伪膜性结肠炎
Gut. 1965 Jun;6(3):207-12. doi: 10.1136/gut.6.3.207.
2
3
Synthesis of intestinal glycoprotein. Incorporation of (I- 14 C) glucosamine in vitro.肠糖蛋白的合成。体外（I-14C）葡糖胺的掺入。
Biochim Biophys Acta. 1971 Feb 28;261(2):353-64.
4
Formation of glucosamine 6-phosphate in regenerating rat liver.
Biochim Biophys Acta. 1971 Aug 19;244(2):311-7. doi: 10.1016/0304-4165(71)90231-5.
5
Intestinal goblet cell mucus: isolation and identification by immunofluorescence of a goblet cell glycoprotein.肠道杯状细胞黏液：通过杯状细胞糖蛋白的免疫荧光法进行分离与鉴定
J Cell Sci. 1973 Mar;12(2):585-602. doi: 10.1242/jcs.12.2.585.
6
Glucosamine synthetase activity of the colonic mucosa in ulcerative colitis and Crohn's disease.溃疡性结肠炎和克罗恩病中结肠黏膜的氨基葡萄糖合成酶活性
Gut. 1977 Mar;18(3):219-28. doi: 10.1136/gut.18.3.219.
7
Intensive intravenous regimen for membranous colitis.
Br Med J. 1976 Aug 7;2(6031):354. doi: 10.1136/bmj.2.6031.354.
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