Neri I, Marzaduri S, Passarini B, Patrizi A
Department of Dermatology, University of Bologna, Italy.
Genitourin Med. 1995 Dec;71(6):410-1. doi: 10.1136/sti.71.6.410.
Porokeratosis of Mibelli is a disorder of epidermal proliferation in which many different clinical forms can be distinguished. Two male patients with a localized type of porokeratosis limited to the genitalia are reported. Later in life they developed an annular skin lesion with peripheral keratotic ridge. The histological examination of a biopsy specimen showed the characteristic features of porokeratosis. There was no family history of similar skin disorders and the patients were not on any drugs. Genital porokeratosis is probably underdiagnosed and we believe that these patients should be followed up on account of the precancerous potential of this disease.
米贝利汗孔角化病是一种表皮增生性疾病，可区分出许多不同的临床类型。本文报告了两名男性患者，他们患有一种局限于生殖器的局限性汗孔角化病。在他们晚年时，出现了一种伴有周边角化性隆起的环形皮肤损害。活检标本的组织学检查显示出汗孔角化病的特征性表现。患者无类似皮肤疾病的家族史，且未服用任何药物。生殖器汗孔角化病可能未得到充分诊断，并且我们认为鉴于这种疾病的癌前潜能，应对这些患者进行随访。
