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移植受者的米贝利汗孔角化症。

Porokeratosis of mibelli in transplant recipients.

作者信息

Komorowski R A, Clowry L J

机构信息

Department of Pathology, Medical College of Wisconsin, Milwaukee 53226.

出版信息

Am J Clin Pathol. 1989 Jan;91(1):71-4. doi: 10.1093/ajcp/91.1.71.

Abstract

Four of 602 renal and hepatic transplant recipients had porokeratosis of Mibelli develop in the posttransplant period. Porokeratosis is an uncommon, autosomally dominant inherited disorder that presents in adolescence as a proliferation of an abnormal clone of epidermal cells. Clinically, it is characterized by nonhealing plaques that develop most commonly on the limbs. Porokeratosis, a premalignant condition, must be added to the list of potential cutaneous complications seen in immunosuppressed organ transplant recipients.

摘要

602名肾移植和肝移植受者中有4人在移植后出现了米贝利汗孔角化症。汗孔角化症是一种罕见的常染色体显性遗传性疾病,在青春期表现为表皮细胞异常克隆的增殖。临床上,其特征是不愈合的斑块,最常见于四肢。汗孔角化症是一种癌前病变,必须列入免疫抑制器官移植受者可能出现的皮肤并发症清单中。

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