Komorowski R A, Clowry L J
Department of Pathology, Medical College of Wisconsin, Milwaukee 53226.
Am J Clin Pathol. 1989 Jan;91(1):71-4. doi: 10.1093/ajcp/91.1.71.
Four of 602 renal and hepatic transplant recipients had porokeratosis of Mibelli develop in the posttransplant period. Porokeratosis is an uncommon, autosomally dominant inherited disorder that presents in adolescence as a proliferation of an abnormal clone of epidermal cells. Clinically, it is characterized by nonhealing plaques that develop most commonly on the limbs. Porokeratosis, a premalignant condition, must be added to the list of potential cutaneous complications seen in immunosuppressed organ transplant recipients.
602名肾移植和肝移植受者中有4人在移植后出现了米贝利汗孔角化症。汗孔角化症是一种罕见的常染色体显性遗传性疾病，在青春期表现为表皮细胞异常克隆的增殖。临床上，其特征是不愈合的斑块，最常见于四肢。汗孔角化症是一种癌前病变，必须列入免疫抑制器官移植受者可能出现的皮肤并发症清单中。
