Xu S, Atchley W R
Department of Botany and Plant Sciences, University of California, Riverside 92521-0124, USA.
J Hered. 1995 Nov-Dec;86(6):477-80. doi: 10.1093/oxfordjournals.jhered.a111625.
Exact formulas that predict the average inbreeding coefficient and heterozygosity of an F2 generation derived from two segregating populations were developed. When population sizes are sufficiently large, the heterozygosity of the F2 is one-half of the heterozygosity of F1 plus one-half of the mean heterozygosity of the two parental populations. The importance of inferring heterozygosity of F2 is discussed from evolutionary perspective.
推导了预测源自两个分离群体的F2代平均近亲繁殖系数和杂合性的精确公式。当群体规模足够大时,F2的杂合性是F1杂合性的一半加上两个亲本群体平均杂合性的一半。从进化角度讨论了推断F2杂合性的重要性。