Espinal M A, Reingold A L, Lavandera M
Division of Public Health Biology and Epidemiology, School of Public Health, University of California, Berkeley 94720-7360, USA.
J Infect Dis. 1996 Feb;173(2):488-91. doi: 10.1093/infdis/173.2.488.
In a case-control study, the effect of recent pregnancy on the risk of developing active tuberculosis among women of reproductive age was investigated in Santo Domingo. Human immunodeficiency virus (HIV)-positive and HIV-negative women diagnosed with new-onset tuberculosis (TB) were compared, respectively, with HIV-positive and HIV-negative women without TB with regard to reproductive history, demographic characteristics, and risk factors for HIV infection. In neither HIV-positive nor HIV-negative women was recent pregnancy or childbirth associated with an increased risk of developing active TB. These results fail to confirm earlier suggestions that pregnancy increases the risk that a woman of child-bearing age infected with Mycobacterium tuberculosis will develop active TB.
在一项病例对照研究中，于圣多明各对近期怀孕对育龄妇女患活动性肺结核风险的影响进行了调查。分别比较了诊断为新发结核病（TB）的人类免疫缺陷病毒（HIV）阳性和HIV阴性女性与未患结核病的HIV阳性和HIV阴性女性在生殖史、人口统计学特征以及HIV感染风险因素方面的情况。在HIV阳性和HIV阴性女性中，近期怀孕或分娩均与患活动性结核病风险增加无关。这些结果未能证实早期的观点，即怀孕会增加感染结核分枝杆菌的育龄妇女患活动性结核病的风险。
