Spinillo A, Capuzzo E, Stronati M, Iasci A, Ometto A, Solerte L
Department of Obstetrics and Gynecology, University of Pavia School of Medicine, Italy.
J Perinat Med. 1995;23(3):175-81. doi: 10.1515/jpme.1995.23.3.175.
We evaluated the rates of short-term neonatal complications, neonatal brain damage or mortality in a group of 96 singleton pregnancies complicated by hypertension and electively delivered before 36 weeks gestation. The neonatal outcome of these pregnancies was compared with that of a matched control group of 192 uneventful pregnancies delivered because of spontaneous preterm labor or premature rupture of membranes. Although the rates of acidosis, apneoic crises, bradycardia and ventilatory support were higher among cases than controls, the risk of intraventricular hemorrhage, severe brain damage (grade III-IV intraventricular hemorrhage or periventricular leucomalacia) or neonatal mortality were comparable between the two groups. Neonatal complications were more frequent among infants born to mothers with severe hypertension or severe proteinuria. In conclusion, this study has shown that short term neonatal complications after elective preterm delivery in hypertensive pregnancies are increased in comparison with low risk controls. However, these complications, which were well managed in our intensive care nursery, did not affected neonatal mortality or severe brain damage.
我们评估了96例单胎妊娠合并高血压且在妊娠36周前选择性分娩的新生儿短期并发症、新生儿脑损伤或死亡率。将这些妊娠的新生儿结局与192例因自然早产或胎膜早破而分娩的无并发症对照妊娠组进行比较。尽管病例组的酸中毒、呼吸暂停危象、心动过缓和通气支持发生率高于对照组,但两组的脑室内出血、严重脑损伤(III-IV级脑室内出血或脑室周围白质软化)或新生儿死亡率风险相当。患有严重高血压或严重蛋白尿的母亲所生婴儿的新生儿并发症更为常见。总之,本研究表明,与低风险对照组相比,高血压妊娠选择性早产术后的短期新生儿并发症有所增加。然而,这些在我们的重症监护病房得到妥善处理的并发症并未影响新生儿死亡率或严重脑损伤。