Tanaka H, Funami M, Sekiguchi S, Narisawa T, Matsuo Y, Moriyasu K, Takaba T
Department of Surgery, Showa University School of Medicine, Tokyo, Japan.
Nihon Geka Gakkai Zasshi. 1995 Nov;96(11):773-8.
To evaluate the influence of coronary artery disease (CAD), we reviewed 102 patients who underwent elective repair of abdominal aortic aneurysm (AAA) between 1982 and 1992. Prior to surgery, all patients underwent clinical evaluation for the presence of CAD including dipyridamole thallium scintigraphy. They were classified into the following groups: Group I (n = 66), no clinical evidence of CAD; Group II (n = 26), clinical evidence of stable CAD; Group III (n = 10), unstable CAD. Coronary angiography (CAG) was performed in group II and group III patients only. All patients in group I and group II underwent elective repair of their AAA without coronary revascularization. Eight patients in group III underwent CABG followed by elective AAA repair within two months. One of two patients who had impending ruptured AAA underwent combined CABG and AAA repair as a single operation and the other underwent AAA repair followed by CABG. One case of perioperative myocardial infarction occurred in group II, but there was no early postoperative death related to cardiac disease in group I and II. In group III, however one patient who underwent combined surgery died of low-output syndrome in the early postoperative period, no death or myocardial infarction occurred following staged operation in the other nine patients. This present results support the contention that CAG is not necessary in all AAA patients, and that they can be managed according to appropriate risk by a selective approach based upon clinical assessment of their CAD. It is also apparent that a staged operation can be performed very safely in patients with unstable CAD.
为评估冠状动脉疾病(CAD)的影响,我们回顾了1982年至1992年间接受腹主动脉瘤(AAA)择期修复术的102例患者。手术前,所有患者均接受了包括双嘧达莫铊闪烁显像在内的CAD临床评估。他们被分为以下几组:第一组(n = 66),无CAD临床证据;第二组(n = 26),稳定CAD临床证据;第三组(n = 10),不稳定CAD。仅对第二组和第三组患者进行了冠状动脉造影(CAG)。第一组和第二组的所有患者均接受了AAA择期修复术,未进行冠状动脉血运重建。第三组的8例患者在两个月内接受了冠状动脉旁路移植术(CABG),随后进行了AAA择期修复术。2例AAA即将破裂的患者中,1例接受了CABG和AAA联合修复术,另1例先接受了AAA修复术,随后进行了CABG。第二组发生了1例围手术期心肌梗死,但第一组和第二组无与心脏疾病相关的早期术后死亡。然而,在第三组中,1例接受联合手术的患者在术后早期死于低心排血量综合征,其他9例患者分期手术后未发生死亡或心肌梗死。目前的结果支持以下观点:并非所有AAA患者都需要进行CAG,可根据对其CAD的临床评估,通过选择性方法根据适当风险进行管理。同样明显的是,不稳定CAD患者可以非常安全地进行分期手术。