de Jongh F E, Ottervanger J P, Stuiver P C
Havenziekenhuis, afd. Inwendige Geneeskunde en Tropische Ziekten, Rotterdam.
Ned Tijdschr Geneeskd. 1996 Jan 6;140(1):37-8.
A 45-year-old woman in the period 1988-1995 suffered three episodes of acute pancreatitis associated with the use of metronidazole. On each occasion the pancreatitis subsided after withdrawal of metronidazole. Pancreatitis is a very infrequent, but potentially dangerous adverse effect of metronidazole. The exact pathogenetic mechanism of metronidazole-induced pancreatitis remains to be determined.
1988年至1995年间,一名45岁女性发生了三次与使用甲硝唑相关的急性胰腺炎。每次在停用甲硝唑后胰腺炎均消退。胰腺炎是甲硝唑一种非常罕见但潜在危险的不良反应。甲硝唑诱发胰腺炎的确切发病机制仍有待确定。