Arredondo de Arreola G, López Serna N, de Hoyos Parra R, Arreola Salinas M A
Departamento de Embriología Facultad de Medicina Universidad Autónoma de Nuevo León, Monterrey, N.L. Mexico.
Otolaryngol Head Neck Surg. 1996 Jan;114(1):54-60. doi: 10.1016/S0194-59989670283-8.
This research describes the development of the lateral nasal wall, the description of which will allow a better comprehension of its anatomic complexity. One hundred embryos and fetuses from the sixth to thirty-sixth weeks of morphologic age were studied. The seventh week shows the first buds of the three turbinates. At the ninth week the precartilaginous nucleus of the inferior turbinate is observed. Likewise, at the tenth week the uncinate process appears, and the invagination of the epithelium begins the formation of the infundibulum and the maxillar sinus. At the fourteenth week the cartilaginous nasal capsule is present. The epithelium is invaginated, starting the formation of the ethmoid cells. During the seventeenth week of development the invagination of the mucus has invaded the maxillar bone, which constitutes the maxillar sinus. At the thirty-sixth week the lateral nasal wall is well developed. In 23 fetuses the supreme turbinate (fourth) was found. Although the length of the lower three turbinates increased progressively and proportionally in intrauterine life without differences between the sexes, the fourth remains invariably at an average length of 5 mm from the fourteenth to the thirty-sixth and was present in 65% of male fetuses.
本研究描述了鼻侧壁的发育过程,对其进行描述有助于更好地理解其解剖复杂性。研究了100例形态学年龄在6至36周的胚胎和胎儿。在第7周时可见三个鼻甲的最初芽体。在第9周时可观察到下鼻甲的软骨前核。同样,在第10周时钩突出现,上皮内陷开始形成漏斗和上颌窦。在第14周时软骨性鼻囊存在。上皮内陷,开始筛窦气房的形成。在发育的第17周,黏液内陷侵入上颌骨,形成上颌窦。在第36周时鼻侧壁发育良好。在23例胎儿中发现了最上鼻甲(第四鼻甲)。虽然在子宫内生活期间下三个鼻甲的长度逐渐且成比例增加,且两性之间无差异,但第四鼻甲从第14周到第36周的平均长度始终为5mm,在65%的男性胎儿中存在。