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可疑暴力犯罪者尿液中蟾蜍色胺(N,N-二甲基-5-羟色胺)的排泄量增加:一项验证性研究。

Urinary excretion of bufotenin (N,N-dimethyl-5-hydroxytryptamine) is increased in suspicious violent offenders: a confirmatory study.

作者信息

Kärkkäinen J, Räisänen M, Huttunen M O, Kallio E, Naukkarinen H, Virkkunen M

机构信息

Peijas Hospital, Vantaa, Finland.

出版信息

Psychiatry Res. 1995 Sep 29;58(2):145-52. doi: 10.1016/0165-1781(95)02747-k.

DOI:10.1016/0165-1781(95)02747-k
PMID:8570766
Abstract

We previously reported that violent offenders with paranoid symptoms or whose violent actions had been directed against family members had higher urinary levels of bufotenin than other violent offenders. In the present study, patients were evaluated with the Karolinska Scales of Personality (KSP), and urinary levels of bufotenin were determined by mass spectrometry. In drug-free patients suspiciousness was positively correlated, and socialization was negatively correlated, with urinary bufotenin excretion. These two personality variables were strongly interdependent. In drug users, bufotenin excretion was correlated positively with social desirability and negatively with irritability, but not with suspiciousness. Bufotenin excretion was not found to be associated with violence toward family members in the present study. The results are in keeping with the earlier finding that violent offenders with paranoid personality traits have higher urinary levels of bufotenin than other violent offenders.

摘要

我们之前曾报道,有偏执症状的暴力罪犯或其暴力行为针对家庭成员的暴力罪犯,其尿液中蟾蜍色胺水平高于其他暴力罪犯。在本研究中,使用卡罗林斯卡个性量表(KSP)对患者进行评估,并通过质谱法测定尿液中蟾蜍色胺的水平。在未使用药物的患者中,怀疑与尿液中蟾蜍色胺排泄呈正相关,社交性与尿液中蟾蜍色胺排泄呈负相关。这两个人格变量密切相关。在吸毒者中,蟾蜍色胺排泄与社会期望呈正相关,与易怒性呈负相关,但与怀疑无关。在本研究中,未发现蟾蜍色胺排泄与对家庭成员的暴力行为有关。这些结果与早期的发现一致,即具有偏执型人格特质的暴力罪犯尿液中蟾蜍色胺水平高于其他暴力罪犯。

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