[由乙肝表面（澳大利亚）抗原-抗体复合物引起的膜性肾小球肾炎]
[Membranous glomerulonephritis caused by HBs (Australia) antigen-antibody complexes].
作者信息
Nagy J, Par A, Bajtai G, Ambus M, Deak G
出版信息
Morphol Igazsagugyi Orv Sz. 1977 Feb;17(1):38-42.
Authors describe a case of chronic aggressive hepatitis with persistent HBs (Australia) antigenaemia and nephrosis syndrome. The renal process microscbically appeared to be membranous glomerulonephritis. By immunofluorescent method antigen deposits IgG, IgM, C3 and HBs of the granular type have been revealed on the glomerular basal membranes. Deposits of the IgA were partially of granular, partially of linear type. Electronmicroscopically on the glomerular basale membrane subepithelial deposits were seen. The results of this study indicate that in the case reported diffuse membranus glomerulonephritis occurred due to HBs antigen-antibody immuno-deposits on the glomerular basal membrane.
作者描述了一例伴有持续性乙肝表面抗原血症和肾病综合征的慢性侵袭性肝炎病例。肾脏病变在显微镜下表现为膜性肾小球肾炎。通过免疫荧光法，在肾小球基底膜上发现了颗粒型的IgG、IgM、C3和乙肝表面抗原沉积。IgA沉积部分为颗粒型，部分为线型。电子显微镜下可见肾小球基底膜上皮下沉积物。本研究结果表明，在该报道病例中，弥漫性膜性肾小球肾炎是由乙肝表面抗原-抗体免疫沉积物在肾小球基底膜上形成所致。
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