Griffiths M H, Thomas D P, Xipell J M, Hope R N
Pathology. 1977 Jan;9(1):43-8. doi: 10.3109/00313027709085237.
A case of transitional cell carcinoma in the left kidney 25 years after urinary tract investigations, and squamous cell carcinoma in the right kidney 6 years later is described. Thorotrast was identified in the kidneys and in the reticulo-endothelial system post mortem and was presumably the contrast material used for the original retrograde pyelogram. When retained in the kidneys after retrograde pyelography Thorotrast produces a characteristic radiological and histological appearance and can be identified by the spectrum of radiation which it emits. The authors believe that this report of bilateral renal carcinomas related to Thorotrast is unique.
本文描述了一例在尿路检查25年后左肾发生移行细胞癌，6年后右肾发生鳞状细胞癌的病例。尸检时在肾脏和网状内皮系统中发现了钍造影剂，推测其为最初逆行肾盂造影所使用的造影剂。逆行肾盂造影后钍造影剂滞留于肾脏时，会产生特征性的放射学和组织学表现，并且可以通过其发射的辐射光谱进行识别。作者认为，这例与钍造影剂相关的双侧肾癌报告是独一无二的。
