Miller G E, Madigan M, Fink R
Bioengineering Program, Texas A&M University, College Station 77843, USA.
Artif Organs. 1995 Jul;19(7):680-4. doi: 10.1111/j.1525-1594.1995.tb02402.x.
Flow patterns in a multiple disk centrifugal pump were analyzed so that the device could be incorporated as a ventricular assist or a bridge-to-transplant device. The pump operates either in pulsatile or steady flow modes with the ability to change modes within a fraction of a second. The pump was tested on a mock circulatory system consisting of an arterial fluid capacitor, a systemic resistor, and a venous capacitor. Arterial volume flow rate, arterial pressure, inlet (venous) pressure, and pump rotation speed are continually monitored. A glycerin/water solution is used as a blood analog. Flow visualization was performed with a 3 mW yellow laser, sheet lens, neutrally buoyant amberlite particles, and both still and motion picture photography. Flow patterns matched theoretical predictions very well; inlet flow spread radially outward through the disk annular spaces while propelled by shear and centrifugal forces.
对多盘离心泵内的流动模式进行了分析，以便该装置能够作为心室辅助装置或移植过渡装置。该泵可在脉动流或稳定流模式下运行，并且能够在几分之一秒内切换模式。该泵在由动脉流体电容器、体循环电阻器和静脉电容器组成的模拟循环系统上进行了测试。持续监测动脉体积流量、动脉压力、入口（静脉）压力和泵的转速。使用甘油/水溶液作为血液模拟物。利用一台3毫瓦的黄色激光器、片状透镜、中性浮力的离子交换树脂颗粒以及静态和动态摄影进行流动可视化。流动模式与理论预测非常吻合；入口流在剪切力和离心力的推动下通过盘状环形空间径向向外扩散。
