Levi H, Sohmer H
Speech and Hearing Center, Hadassah University Hospital, Jerusalem, Israel.
J Basic Clin Physiol Pharmacol. 1995;6(2):129-38. doi: 10.1515/jbcpp.1995.6.2.129.
There are conflicting findings concerning whether auditory nerve-brainstem evoked response (ABR) interpeak latencies (e.g. brainstem transmission time - BTT) are constant in response to different stimulus intensities. In order to study the effects of click intensity on the BTT, and to try to determine the mechanism of such an effect, ABR was recorded from 10 adult white Sabra rats in response to different click intensities. The stimulus intensity was reduced from the highest intensity generated by the equipment until no responses could be obtained. Band-reject (notched) noise was presented simultaneously with the clicks in order to restrict the region of basilar membrane activation. BTT decreased with decreasing click intensity and this was accompanied by a prolongation of the latency of wave I to a greater extent than that of wave IV. At high and intermediate intensities, wave I appeared as two split peaks. These effects were not abolished by the restricting notched noise. Possible mechanisms of these latency changes are considered.
关于听神经-脑干诱发电位（ABR）的峰间潜伏期（如脑干传导时间 - BTT）在不同刺激强度下是否恒定，存在相互矛盾的研究结果。为了研究短声强度对BTT的影响，并试图确定这种影响的机制，对10只成年白色Sabra大鼠进行记录，以响应不同强度的短声刺激。刺激强度从设备产生的最高强度逐渐降低，直至无法获得反应。在短声刺激的同时呈现带阻（陷波）噪声，以限制基底膜激活区域。BTT随短声强度降低而减小，同时I波潜伏期的延长程度大于IV波。在高强度和中等强度下，I波呈现为两个分裂峰。这些效应并未因带阻噪声的限制而消除。文中考虑了这些潜伏期变化的可能机制。
