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Inhibition of bacterial growth in vitro by human ejaculate seminal plasma fraction 1 and its possible practical use in male infertility phenomenon.

作者信息

Marcus Z H, Lewin L M, Ginsberg R

机构信息

Blood Bank, Edith Wolfson Medical Center, Holon, Israel.

出版信息

J Assist Reprod Genet. 1995 Aug;12(7):443-6. doi: 10.1007/BF02211145.

DOI:10.1007/BF02211145
PMID:8574072
Abstract

PURPOSE

The in vitro bacteriostatic effect on bacteria by a fraction of human ejaculate (HuSePl-Fr1) was studied.

METHOD

As bacterial indicators, Pseudomonas aeruginosa (Pa), total coliforms (Tc), fecal coliforms (Fc), Escherichia coli (Ec), and Staphylococcus aureus (Sa) were used. These bacterial strains are known as agents that cause urinary and sexually transmitted infections (STI).

RESULTS

Preliminary results suggest that HuSePl-Fr1 has a significant in vitro bacteriostatic effect on Pa and Sa at 42 degrees C. In addition, Pa was inhibited at 37 degrees C after 48 hr incubation. The remaining bacterial indicators were not affected.

CONCLUSION

The results indicate a possible protective role of HuSePl-Fr1 in treatment of infertile men due to genital infections.

摘要

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本文引用的文献

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Studies on immune infertility: a hypothesis on the etiology of immune infertility based on the biological role of seminal plasma immune response inhibitor.免疫性不孕的研究：基于精浆免疫反应抑制剂生物学作用的免疫性不孕病因假说
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In vitro studies in reproductive immunology. - 2. Demonstration of the inhibitory effect of male genital tract constituents on PHA-stimulated mitogenesis and E-rosette formation of human lymphocytes.
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