Dedhiya S, Kong S X
Department of Pharmacy Administration, College of Pharmacy, University of Illinois at Chicago 60612, USA.
Pharm World Sci. 1995 Sep 22;17(5):141-8. doi: 10.1007/BF01879707.
This paper summarizes the concepts and measures of quality of life. Although numerous attempts have been made to conceptualize and operationalize quality of life, there has been no universally accepted standard for the study design, data collection and data analysis of studies that use quality of life as an outcome measure. Quality of life has been defined either as a measure of happiness and satisfaction with life, or goal achievement, or social utility. However, most studies conceptualize and measure quality of life as a composite that consists of several domains. There are two approaches to the measurement of quality of life, namely, the psychometric approach and the utility approach. A quality of life measure can be either generic or disease-specific. High reliability and validity are important criteria for a credible quality of life instrument. Published clinical studies which use quality of life as an outcome measure have to be assessed on the basis of the appropriateness of the study design, the validity of study results and the applicability of the quality of life measure to the specific patient group.
本文总结了生活质量的概念和衡量方法。尽管人们多次尝试对生活质量进行概念化和操作化，但对于将生活质量作为结果指标的研究的设计、数据收集和数据分析，尚无普遍接受的标准。生活质量要么被定义为对生活的幸福和满意度的衡量，要么被定义为目标达成情况，要么被定义为社会效用。然而，大多数研究将生活质量概念化为并衡量为由几个领域组成的综合指标。生活质量的测量有两种方法，即心理测量法和效用法。生活质量测量指标可以是通用的，也可以是疾病特异性的。高信度和效度是可信的生活质量工具的重要标准。以生活质量作为结果指标的已发表临床研究必须根据研究设计的恰当性、研究结果的效度以及生活质量测量指标对特定患者群体的适用性来进行评估。
