Enomoto N, Sato C
Second Dept of Internal Medicine, Faculty of Medicine, Tokyo Medical and Dental University, Japan.
Trends Microbiol. 1995 Nov;3(11):445-7. doi: 10.1016/s0966-842x(00)89000-9.
Hepatitis C virus populations in infected individuals consist of quasispecies with diverse mutations. These quasispecies have different biological properties, and the analysis of these variants has led to new interpretations of viral persistence, carcinogenesis and resistance to interferon therapy.
受感染个体中的丙型肝炎病毒群体由具有不同突变的准种组成。这些准种具有不同的生物学特性，对这些变体的分析为病毒持续存在、致癌作用及对干扰素治疗的抗性带来了新的解释。
