Anatoliĭ S A, Kokriakov V N, Iunusova M I, Veretilenko V E, Volkova L P
Zh Mikrobiol Epidemiol Immunobiol. 1977 Mar(3):71-4.
A study was made of the bactericidal action of thymus histones, histone-like substance, from the nuclei of rabbit leukocytes and lysosomal cation proteins from the same leukocyte on different staphylococcus cultures. The majority of the strains of coagulasoneagative staphylococci perished under the effect of the preparations tested; cultures forming this enzyme retained their viability, irrespective of their virulence for mice, their capacity to the lecithinase formation and to mannite fermentation. The preparations studied possessed a different bactericidal activity. It is supposed that there existed an correlation between the sensitivity of staphylococcus strains to the antimicrobial action of the leukocytic cation proteins and the index of phagocytosis completion of hese microbes.
对来自兔白细胞细胞核的胸腺组蛋白、类组蛋白物质以及来自同一白细胞的溶酶体阳离子蛋白对不同葡萄球菌培养物的杀菌作用进行了研究。大多数凝固酶阴性葡萄球菌菌株在受试制剂的作用下死亡；产生这种酶的培养物保持其活力，无论它们对小鼠的毒力、形成卵磷脂酶的能力以及对甘露醇发酵的能力如何。所研究的制剂具有不同的杀菌活性。据推测，葡萄球菌菌株对白细胞阳离子蛋白抗菌作用的敏感性与这些微生物吞噬作用完成指数之间存在相关性。
