Utin A V
Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(3):267-71.
By means of clinico-catamnestical and anthropological methods the author examined 162 epileptic patients in the initial period (up to 5 years) and 473--in the florid period of the disease (5--24 years). The author demonstrates distinct clinical (the traits of the onset, development of the process, personality changes, invalidization), morphological (dysgenesia) and premorbid characterological and intellectual traits in patients of consanguineous and nonconsanguineous families. The results demonstrate a correlation between the fenotypical traits of epilepsy and the constitutional morphological and premorbid features. The achieved data point to the necessity of a differentiated approach to therapeutical measures and sociolabour rehabilitation in patients of consanguineous and nonconsanguineous families.
作者通过临床随访和人类学方法，对162例处于疾病初期（5年以内）的癫痫患者以及473例处于疾病活跃期（5 - 24年）的癫痫患者进行了检查。作者展示了近亲家庭和非近亲家庭患者在临床（发病特征、病程发展、人格改变、致残情况）、形态学（发育异常）以及病前性格和智力特征方面的明显差异。结果表明癫痫的表型特征与体质形态学和病前特征之间存在相关性。所获得的数据表明，对于近亲家庭和非近亲家庭的患者，在治疗措施和社会劳动康复方面需要采取差异化方法。
