García-Río F, Pino J M, Casadevall J, Gómez L, Atienza J M, Díaz-Lobato S, Villamor J
Service of Respiratory Diseases, La Paz Hospital, School of Medicine, Autonoma University, Madrid, Spain.
J Comput Assist Tomogr. 1996 Jan-Feb;20(1):20-3. doi: 10.1097/00004728-199601000-00005.
Our goal was to assess the usefulness of spirometry to estimate the risk of pneumothorax in patients undergoing percutaneous needle biopsy with CT guidance for solitary pulmonary nodule (SPN).
We studied the results of 51 consecutive percutaneous needle biopsies with CT guidance for SPN obtained between 1988 and 1990. Forty-five men and six women, aged 65 +/- 11 (36-86) years, were included in the study. All biopsies were performed under CT guidance, with 90 mm 25G needles (0.5 mm thickness) fitted into luer-type syringes. The number of needle pass attempts never exceeded three. A spirometry before biopsy was performed in all patients.
Pneumothorax occurred in only 10 cases (19%). The patients with pneumothorax showed lower lesion size, forced vital capacity (FVC), forced expiratory volume (FEV1), and FEV1/FVC ratio. The contribution of these factors to pneumothorax was analyzed by a logistic regression model. The FEV1 was most strongly associated with the incidence of pneumothorax. We developed an equation for predicting the risk of this complication.
We conclude that decreasing FEV1 is associated with a higher pneumothorax rate.
我们的目标是评估在CT引导下对孤立性肺结节（SPN）进行经皮针吸活检的患者中，肺功能测定对估计气胸风险的有用性。
我们研究了1988年至1990年间连续51例在CT引导下对SPN进行经皮针吸活检的结果。研究纳入了45名男性和6名女性，年龄为65±11（36 - 86）岁。所有活检均在CT引导下进行，使用90毫米25G针（0.5毫米厚）安装在鲁尔型注射器上。针穿刺尝试次数从未超过三次。所有患者在活检前均进行了肺功能测定。
仅10例（19%）发生气胸。发生气胸的患者病变大小、用力肺活量（FVC）、用力呼气量（FEV1）和FEV1/FVC比值较低。通过逻辑回归模型分析了这些因素对气胸的影响。FEV1与气胸发生率的相关性最强。我们建立了一个预测这种并发症风险的方程。
我们得出结论，FEV1降低与较高的气胸发生率相关。
