Department of Radiology, School of Medicine, Duzce University, Duzce, Turkey.
Wien Klin Wochenschr. 2011 Feb;123(3-4):79-82. doi: 10.1007/s00508-011-1538-y. Epub 2011 Feb 17.
Transthoracic biopsy (TTB) is a well-defined and effective method used for pathologic sampling in the diagnosis of the pulmonary lesions. It is less invasive in comparison to surgical procedures. In addition, diagnostic rate of tru-cut biopsy is higher than that of fine needle aspiration biopsy (FNAB) especially for benign lesions. In this study, we presented tru-cut transthoracic biopsy (TTB) procedure results and the frequency of TTB complications with related risk factors.
A total of 102 patients were evaluated by CT scan guided tru-cut TTB in the diagnosis of lung lesions between January 2003 and December 2007. The complications due to tru-cut TTB were recorded. The factors such as the lesion depth, the lesion size, and the emphysematous changes that accompany the lesion were evaluated through χ(2) test.
Among the samples, 51% malignancy and 49% benign pathology were observed. Pneumothorax developed in 15.7% of the 102 procedures. It was found that the lesion's distance from the pleura, the size of the lesion, and emphysematous changes around the lesion significantly increased the risk of pneumothorax.
The tru-cut biopsy complications are similar to those of FNAB. In the centers where cytologic examination is insufficient in the diagnosis of lung lesions, tru-cut biopsy should be routinely performed as it is a reliable biopsy technique compared to FNAB.
经胸活检（TTB）是一种明确且有效的方法，用于诊断肺部病变时进行病理采样。与外科手术相比，它的侵入性更小。此外，与细针抽吸活检（FNAB）相比， tru-cut 活检的诊断率更高，尤其是对于良性病变。在这项研究中，我们展示了 tru-cut 经胸活检（TTB）的操作结果以及 TTB 并发症的发生频率及其相关的危险因素。
2003 年 1 月至 2007 年 12 月，我们对 102 例 CT 扫描引导下 tru-cut TTB 诊断肺部病变的患者进行评估。记录 tru-cut TTB 相关并发症。通过卡方检验评估病变深度、病变大小以及病变周围肺气肿改变等因素与 tru-cut TTB 并发症的关系。
在所有标本中，51%为恶性，49%为良性病变。102 例中有 15.7%发生气胸。结果表明，病变距胸膜的距离、病变大小和病变周围肺气肿的改变显著增加了气胸的风险。
tru-cut 活检的并发症与 FNAB 相似。在细胞学检查不足以诊断肺部病变的中心，与 FNAB 相比，tru-cut 活检作为一种可靠的活检技术，应该常规进行。
