Kudrna G R, Stanley M A, Remington L A
J Am Optom Assoc. 1995 Nov;66(11):675-80.
The effects of miotic drugs on visual field sensitivity have been well documented, but few studies have reported the effects of active pupillary dilation on visual field sensitivity. Since visual field testing is sometimes performed when a patient is undergoing pupillary dilation for fundus examination, the effects of active pupillary dilation is of concern to today's optometrist.
The effects of active pupillary dilation on automated static threshold perimetry were studied in 23 normal subjects using the Humphrey Field Analyzer and the 30-2, StatPac, and FastPac programs. Baseline automated perimetry was performed on both eyes of each subject with the Humphrey Field Analyzer. On a separate visit, automated perimetry was performed on both eyes of all subjects while each eye was undergoing active pupillary dilation. Baseline and dilated visual field parameters were compared.
A decrease in foveal threshold of 1.95 decibels (p = 0.0081), a mean deviation loss of 1.15 decibels (p = 0.0001), a decrease in short-term fluctuation (SF) of 0.19 decibels (p = 0.0423), and a decrease in the SF2 of 0.56 decibels (p = 0.0374) were found in the dilated fields as compared with the baseline visual fields in the first eye tested. A decrease in foveal threshold of 2.56 decibels (p = 0.0081) and a mean deviation loss of 1.43 decibels (p = 0.0001) were found in the dilated fields as compared with the baseline visual fields in the second eye tested.
These findings indicate that active pupillary dilation in healthy subjects produces statistically significant differences, although these differences may not be clinically significant. To ensure repeatable visual fields, consistent pupil diameter should be controlled during serial visual field testing.
缩瞳药物对视野敏感度的影响已有充分记录，但很少有研究报道主动瞳孔散大对视野敏感度的影响。由于有时在患者因眼底检查而进行瞳孔散大时进行视野测试，主动瞳孔散大的影响是当今验光师所关注的。
使用 Humphrey 视野分析仪以及 30 - 2、StatPac 和 FastPac 程序，对 23 名正常受试者研究主动瞳孔散大对自动静态阈值视野检查的影响。用 Humphrey 视野分析仪对每个受试者的双眼进行基线自动视野检查。在另一次就诊时，对所有受试者的双眼进行自动视野检查，同时每只眼睛正在进行主动瞳孔散大。比较基线和散大后的视野参数。
与测试的第一只眼睛的基线视野相比，散大后的视野中发现中央凹阈值降低了 1.95 分贝（p = 0.0081），平均偏差损失 1.15 分贝（p = 0.0001），短期波动（SF）降低了 0.19 分贝（p = 0.0423），SF2 降低了 0.56 分贝（p = 0.0374）。与测试的第二只眼睛的基线视野相比，散大后的视野中发现中央凹阈值降低了 2.56 分贝（p = 0.0081），平均偏差损失 1.43 分贝（p = 0.0001）。
这些发现表明，健康受试者的主动瞳孔散大会产生统计学上的显著差异，尽管这些差异可能在临床上不显著。为确保可重复的视野检查，在系列视野测试期间应控制一致的瞳孔直径。
