Bowen W P, Jerman J C
Department of Neuroscience, SmithKline Beecham Pharmaceuticals, Harlow, UK.
Trends Pharmacol Sci. 1995 Dec;16(12):413-7. doi: 10.1016/s0165-6147(00)89091-4.
Pharmacologists are often required to analyse nonlinear experimental effects by fitting the data to defined theoretical models. This may require a specialized computer program capable of performing nonlinear regression analysis, which can prove costly given the variety of pharmacological research. Here, Wayne Bowen and Jeff Jerman describe a generic method of performing nonlinear regression using spreadsheet applications, and demonstrate how this approach can be used to create automated systems of data analysis.
药理学家常常需要通过将数据拟合到特定的理论模型来分析非线性实验效应。这可能需要一个能够执行非线性回归分析的专业计算机程序,鉴于药理研究的多样性,这可能成本高昂。在此,韦恩·鲍恩和杰夫·杰曼描述了一种使用电子表格应用程序进行非线性回归的通用方法,并展示了如何使用这种方法创建自动化数据分析系统。