异基因骨髓移植治疗一名嗜酸性粒细胞增多综合征患者。
Allogeneic bone marrow transplantation in a patient with hypereosinophilic syndrome.
作者信息
Esteva-Lorenzo F J, Meehan K R, Spitzer T R, Mazumder A
机构信息
Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.
出版信息
Am J Hematol. 1996 Feb;51(2):164-5. doi: 10.1002/(SICI)1096-8652(199602)51:2<164::AID-AJH12>3.0.CO;2-I.
We describe a 32-year-old man with idiopathic hypereosinophilic syndrome (HES) who presented with pulmonary dysfunction, thrombocytopenia, lymphadenopathy, and hepatosplenomegaly. The patient developed progressive disease on prednisone and hydroxyurea therapy, and he underwent a successful allogeneic bone marrow transplantation (BMT). The patient is asymptomatic with no evidence of eosinophilia 30 months after transplantation. There is currently no cure for patients with HES, and BMT should be considered in selected patients.
我们描述了一名32岁患有特发性嗜酸性粒细胞增多综合征（HES）的男性，他出现了肺功能障碍、血小板减少、淋巴结病和肝脾肿大。该患者在接受泼尼松和羟基脲治疗后病情进展，随后成功接受了异基因骨髓移植（BMT）。移植后30个月，患者无症状，且无嗜酸性粒细胞增多的证据。目前HES患者尚无治愈方法，对于选定的患者应考虑进行BMT。
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