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颞骨治疗性放射的非骨炎并发症。

Non-osteitic complications of therapeutic radiation to the temporal bone.

作者信息

Smouha E E, Karmody C S

机构信息

Department of Surgery, School of Medicine, State University of New York at Stony Brook 11794-8191, USA.

出版信息

Am J Otol. 1995 Jan;16(1):83-7.

PMID:8579183
Abstract

The temporal bone often falls within the field of radiation for head and neck tumors. Whereas osteoradionecrosis is well recognized as the end-stage complication of radiation to the temporal bone, serious non-osteitic complications can also occur, and these are important because the ear is an organ of special sense. Radiation causes changes in the specialized tissues of the ear that can impair function and influence therapeutic decisions. The purpose of this article is to review the non-osteitic effects of radiation on the ear. A series of cases is presented that illustrate the spectrum of non-osteitic complications of radiation therapy. External canal stenosis, otitis media with effusion, chronic suppurative otitis media with or without cholesteatoma, sensorineural hearing loss, vestibular impairment, and facial nerve paralysis are described. Management should be guided by an understanding of the pathogenesis of these complications. The authors believe that non-osteitic complications of therapeutic radiation to the temporal bone are relatively common and warrant increased recognition.

摘要

颞骨常处于头颈部肿瘤的放射野内。虽然骨放射性坏死是颞骨放疗的终末期并发症已广为人知,但严重的非骨炎并发症也可能发生,而这些并发症很重要,因为耳是特殊感觉器官。放疗会引起耳部特殊组织的变化,这可能损害功能并影响治疗决策。本文的目的是综述放疗对耳部的非骨炎影响。文中呈现了一系列病例,以说明放射治疗非骨炎并发症的范围。描述了外耳道狭窄、渗出性中耳炎、伴或不伴胆脂瘤的慢性化脓性中耳炎、感音神经性听力损失、前庭功能损害及面神经麻痹。应基于对这些并发症发病机制的理解来进行处理。作者认为,颞骨治疗性放疗的非骨炎并发症相对常见,值得更多关注。

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引用本文的文献

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External Auditory Canal Cholesteatoma after Radiation Therapy for Nasopharyngeal Cancer: Case Series and Systematic Review.鼻咽癌放射治疗后外耳道胆脂瘤:病例系列与系统评价
J Clin Med. 2023 Mar 2;12(5):1977. doi: 10.3390/jcm12051977.
2
Radiation Necrosis of the Lateral Skull Base and Temporal Bone.侧颅底和颞骨的放射性坏死
Semin Plast Surg. 2020 Nov;34(4):265-271. doi: 10.1055/s-0040-1721763. Epub 2020 Dec 24.
3
Osteoradionecrosis of the temporal bone: a case series.颞骨放射性骨坏死:病例系列
Otol Neurotol. 2014 Aug;35(7):1207-17. doi: 10.1097/MAO.0000000000000321.
4
Squamous papilloma in the external auditory canal: A common lesion in an uncommon site.外耳道鳞状乳头状瘤:一个罕见部位的常见病变。
World J Clin Cases. 2013 May 16;1(2):92-5. doi: 10.12998/wjcc.v1.i2.92.
5
Audiological findings in patients treated with radiotherapy for head and neck tumors.头颈部肿瘤放疗患者的听力学发现。
Braz J Otorhinolaryngol. 2010 Jul-Aug;76(4):527-32. doi: 10.1590/S1808-86942010000400019.