Pavlovskaia A I, Probatova N A
Arkh Patol. 1995 Sep-Oct;57(5):21-5.
Immunoblastic lymphadenitis is a T-cell immune hyper-response to antigenic stimulation. Patho-histologically, polymorphic hyperplasia of the lymph node pulp with a widening of the paracortical zone and the disturbance of the node structure is found. The cells of the paracortical proliferate are represented by small lymphocytes, stimulated lymphoid cells of varying size with numerous immunoblasts, plasma cells at various stages of maturation including lymphoplasmocytoid ones. When the structure of the lymph node is disturbed immunohistochemical examination is necessary to reject malignant lymphoma.
免疫母细胞性淋巴结炎是机体对抗原刺激的一种T细胞免疫反应亢进。病理组织学上，可见淋巴结髓质多形性增生，副皮质区增宽，淋巴结结构紊乱。副皮质区增生的细胞包括小淋巴细胞、大小不一的受刺激淋巴细胞以及大量免疫母细胞、处于不同成熟阶段的浆细胞，包括淋巴浆细胞样细胞。当淋巴结结构紊乱时，需进行免疫组化检查以排除恶性淋巴瘤。
