Hori C, Tsukahara H, Fujii Y, Kawamitsu T, Konishi Y, Yamamoto K, Ishii Y, Sudo M
Department of Pediatrics, Fukui Medical School, Japan.
Biol Neonate. 1995;68(4):254-8. doi: 10.1159/000244243.
To elucidate the long-term consequences of osteopenia of prematurity, lumbar spinal bone mass was measured in 21 preterm-born children aged 3-4 years by dual-energy X-ray absorptiometry. Their mineral intake remained low during early life, and all 11 infants previously studied were osteopenic at term postconception. At the age of 3-4 years, however, all 21 children were found to have normal bone mineral content and density with slightly elevated serum osteocalcin levels. Our results show that in preterm-born children spontaneous resolution of lumbar spinal osteopenia occurs during early childhood.
为了阐明早产骨质减少的长期后果，通过双能X线吸收法对21名3 - 4岁的早产儿童进行了腰椎骨量测量。他们在生命早期的矿物质摄入量一直较低，之前研究的所有11名婴儿在孕龄足月时均为骨质减少。然而，在3 - 4岁时，发现所有21名儿童的骨矿物质含量和密度均正常，血清骨钙素水平略有升高。我们的结果表明，早产儿童腰椎骨质减少在幼儿期会自发缓解。
