Tsukahara H, Sudo M, Umezaki M, Fujii Y, Kuriyama M, Yamamoto K, Ishii Y
Department of Pediatrics, Radiology, Fukui Medical School, Japan.
Biol Neonate. 1993;64(2-3):96-103. doi: 10.1159/000243978.
Lumbar spinal bone mineral density (BMD) was measured in 40 preterm infants by dual-energy X-ray absorptiometry (DXA). During the first several months of life, their BMD was considerably lower than that of normal term infants and the osteopenia was more pronounced in the more preterm and smaller infants. Weak (inverse) correlations were found between the BMD and urinary calcium/creatinine or tubular phosphorus reabsorption ratio. Rickets-like changes in the forearm bones did not predict the greater spinal osteopenia. Follow-up study was performed in 10 preterms. In 3 of the 4 who underwent the last DXA between 8 and 12 months, BMD had improved remarkably. Our present study shows the potential of DXA for the assessment and management of osteopenia of prematurity.
采用双能X线吸收法（DXA）对40例早产儿进行腰椎骨密度（BMD）测量。在出生后的头几个月，他们的骨密度明显低于足月儿，且早产程度越高、体重越小的婴儿骨质减少越明显。骨密度与尿钙/肌酐或肾小管磷重吸收率之间存在弱（负）相关性。前臂骨骼的佝偻病样改变并不能预测更严重的脊柱骨质减少。对10例早产儿进行了随访研究。在8至12个月期间接受最后一次DXA检查的4例中，有3例的骨密度有显著改善。我们目前的研究表明DXA在评估和管理早产儿骨质减少方面具有潜力。
