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挪威宫颈癌大规模筛查:试点项目评估

Mass screening for cervical cancer in Norway: evaluation of the pilot project.

作者信息

Bjørge T, Gunbjørud A B, Haugen O A, Skare G B, Tropé C, Thoresen S O

机构信息

Cancer Registry of Norway, Oslo.

出版信息

Cancer Causes Control. 1995 Nov;6(6):477-84. doi: 10.1007/BF00054154.

Abstract

The Norwegian Department of Health and Social Affairs initiated a national screening program for cervical cancer in 1990, with all women aged 25 to 70 years to be offered cervical screening every three years. During the first three years of the program (November 1991-October 1994), all spontaneous cervical cytology in Norway was recorded at the Norwegian Cancer Registry. In addition, women in the counties of Vestfold and Sør-Trøndelag were invited individually to be screened. The aim of the present study was principally to evaluate the organization aspects of a nationwide, population-based screening program for cervical cancer in Norway. Special attention was paid to the coverage, the attendance rate, and the cytologic findings in the two-county study area. A total of 1,581,379 Pap smears were recorded from November 1991 to October 1994. Most smears were taken from women under age 30 years (31.7 percent). About 25 percent of the women aged 25 to 29 years had more than one normal smear. In the study area, a coverage of about 71 percent in the age group 25 to 69 years was achieved. The pilot project also has shown that it is possible to recruit elderly women into screening. However, no difference was noted between the study and the reference area with regard to findings per smear of precursor lesions (CIN 3, modified SNOMED coding system). The experiences from three years of recording and the implementation of the pilot project have provided useful guidelines for the national screening which began in January 1995.

摘要

挪威卫生和社会事务部于1990年启动了一项全国性宫颈癌筛查计划,为所有25至70岁的女性每三年提供一次宫颈癌筛查。在该计划的头三年(1991年11月至1994年10月),挪威所有自发的宫颈细胞学检查记录都保存在挪威癌症登记处。此外,韦斯特福尔郡和南特伦德拉格郡的女性被单独邀请参加筛查。本研究的主要目的是评估挪威全国性、基于人群的宫颈癌筛查计划的组织方面。特别关注两郡研究区域的覆盖率、参与率和细胞学检查结果。1991年11月至1994年10月共记录了1,581,379份巴氏涂片。大多数涂片取自30岁以下的女性(31.7%)。25至29岁的女性中约有25%有不止一次正常涂片。在研究区域,25至69岁年龄组的覆盖率约为71%。该试点项目还表明,有可能招募老年女性参与筛查。然而,在研究区域和参照区域之间,每涂片的前驱病变(CIN 3,改良的SNOMED编码系统)检查结果没有差异。三年记录和试点项目实施的经验为1995年1月开始的全国性筛查提供了有用的指导方针。

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