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消化性溃疡:手术治疗的晚期并发症

[Peptic ulcer: late complications of the surgical treatment].

作者信息

Pinatel Lopasso F

机构信息

Cirugía de la Universidad de Sao Paulo, Brasil.

出版信息

Rev Gastroenterol Peru. 1995 Sep-Dec;15(3):273-81.

PMID:8580456
Abstract

The incidence of surgical treatment of peptic ulcer decreased in the last two decades. The majority of procedures for surgical management of peptic disease impairs the ability of the stomach to receive and to store food. The intake of high protein-caloric content diets can improve some nutritional deficits expressed by loss of body weight and anemia. The mechanism responsible for diarrhea is unknown, but truncal vagotomy has the highest incidence. It is usually episodic, lessens over the first year after operation and rarely remains a severe problem. The decreasing levels of colecistokinin response after meal in gastrectomy and the division of hepatic branch of anterior vagus can cause gallbladder sludge and stone formation. Alkaline reflux explains gastritis and esophagitis after partial gastric resection. Surgical duodenal diversion, like a Roux-en-Y limb, have been successful in its control. The mechanism that leads to the dumping syndrome are loss of gastric reservoir function and rapid emptying of hyperosmolar meals into small intestine. Somatostatin analogues improve the symptoms caused by abnormal release of neurohormonal agents responsible of the behaviour of the gastrointestinal tract after meals. Cancer of gastric remanent may be due to increased bacterial overgrowth and nitrosation formation. The endoscopic follow-up is essential for early diagnosis of the stump cancer. In spite of all complications, the surgeon cannot have hesitations by carrying out radical approach meanly during catastrophic emergencies of peptic disease i.e. in elderly aged patients. Nowadays, the control of chronic sequelas is easy with conservative therapeutic.

摘要

在过去二十年中,消化性溃疡的手术治疗发生率有所下降。大多数消化性疾病的手术治疗方法会损害胃接收和储存食物的能力。摄入高蛋白高热量饮食可以改善因体重减轻和贫血所表现出的一些营养缺乏状况。腹泻的发病机制尚不清楚,但迷走神经干切断术的发生率最高。腹泻通常呈发作性,在术后第一年有所减轻,很少会一直是严重问题。胃切除术后餐后胆囊收缩素反应水平降低以及迷走神经前干肝支的离断可导致胆囊淤积和结石形成。碱性反流可解释部分胃切除术后的胃炎和食管炎。手术性十二指肠改道,如 Roux-en-Y 吻合术,已成功控制了这种情况。导致倾倒综合征的机制是胃储存功能丧失以及高渗性食物快速排空进入小肠。生长抑素类似物可改善因神经激素异常释放所引起的症状,这些神经激素负责餐后胃肠道的行为。残胃癌可能是由于细菌过度生长和亚硝化作用增加所致。内镜随访对于残胃癌的早期诊断至关重要。尽管存在所有这些并发症,但在消化性疾病的灾难性紧急情况下,即老年患者中,外科医生在进行根治性手术时不能有丝毫犹豫。如今,通过保守治疗很容易控制慢性后遗症。

相似文献

1
[Peptic ulcer: late complications of the surgical treatment].消化性溃疡:手术治疗的晚期并发症
Rev Gastroenterol Peru. 1995 Sep-Dec;15(3):273-81.
2
Total gastrectomy reconstructed by interposition of a jejunal J pouch with preservation of hepatic vagus branch and lower esophageal sphincter for T2 gastric cancer without lymph node metastasis.对于无淋巴结转移的T2期胃癌,通过插入空肠J形贮袋进行全胃切除术,同时保留肝迷走神经分支和食管下括约肌。
Hepatogastroenterology. 2004 Jul-Aug;51(58):1233-40.
3
Gastric stump cancer after stomach resection due to peptic disease.因消化性疾病行胃切除术后发生的残胃癌。
Chir Ital. 1996;48(4):9-12.
4
The early postprandial dumping syndrome: prevention and treatment.早期餐后倾倒综合征:预防与治疗
Major Probl Clin Surg. 1976;20:14-27.
5
Surgical treatment of peptic ulceration.消化性溃疡的外科治疗。
Curr Opin Gen Surg. 1993:206-15.
6
[Diagnosis, prevention and treatment of postoperative reflux gastritis].[术后反流性胃炎的诊断、预防与治疗]
Khirurgiia (Mosk). 1994 May(5):32-5.
7
Roux-en-Y syndrome after surgical treatment of alkaline reflux gastritis.碱性反流性胃炎手术治疗后的Roux-en-Y综合征
Rev Esp Enferm Dig. 1999 Nov;91(11):748-58.
8
[Current ulcer surgery from the internist's view point: vagotomy versus resection].[从内科医生视角看当前的溃疡手术:迷走神经切断术与切除术]
Fortschr Med. 1977 Aug 11;95(30):1851-4.
9
[Radionuclide study of gastric emptying in patients who have undergone Roux-en-Y gastrojejunostomy for postoperative alkaline gastritis].[接受Roux-en-Y胃空肠吻合术治疗术后碱性胃炎患者的胃排空放射性核素研究]
Rev Esp Med Nucl. 1998;17(5):358-64.
10
Helicobacter pylori infection after gastrectomy and vagotomy in duodenal ulcer patients.十二指肠溃疡患者胃切除及迷走神经切断术后的幽门螺杆菌感染
J Physiol Pharmacol. 1996 Mar;47(1):229-37.

引用本文的文献

1
Dumping Syndrome: A Review of the Current Concepts of Pathophysiology, Diagnosis, and Treatment.倾倒综合征:当前病理生理学、诊断及治疗概念综述
Dig Dis Sci. 2016 Jan;61(1):11-8. doi: 10.1007/s10620-015-3839-x. Epub 2015 Sep 22.