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早期餐后倾倒综合征:预防与治疗

The early postprandial dumping syndrome: prevention and treatment.

作者信息

Woodward E R, Bushkin F L

出版信息

Major Probl Clin Surg. 1976;20:14-27.

PMID:957778
Abstract

The early postprandial dumping syndrome can be prevented or minimized by the appropriate selection of the operative procedure to fit the patient and the peptic ulcer problem he presents, and by proper attention to diet in the early postoperative period. When it does occur, the syndrome usually responds favorably to dietary management and tends to spontaneously regress in severity with time. For these reasons further surgery is seldom required for the early postprandial dumping syndrome. In the patient who fails to improve with diet therapy and time and has disabling symptoms often accompanied by progressive malnutrition, revisional surgery should be undertaken. It is the objective of the surgeon to alter the reconstruction in such a way that emptying from the stomach or gastric remnant is delayed. Therefore, the upper small intestine dose not receive a large, rapidly introduced hyperosmolar bolus to initiate the release of humoral substances causing the syndrome. All revisions utilized are potentially ulcerogenic and if vagotomy has not been a part of the original procedure, it should routinely be performed at the time of revision. Patients who have primarily has a Billroth II gastrectomy will frequently improve markedly with simple conversion to a Billroth I reconstruction. This is particularly true when the residual stomach is moderately large (i.e., after antrectomy) and when the gastrojejunal stoma is larger in diameter than the normal jejunum. Under such circumstances approximately 80 per cent of patients will improve sufficiently so that a more complex procedure need not be utilized at once. Under all other conditions we prefer a 10 cm. segment of reversed jejunum anastomosed proximally to the gastric stump and distally to a 40 cm. isoperistaltic Roux-en-Y jejunal limb. This procedure is so successful that one can justify its use as first recourse even in the anatomically favorable Billroth II patient. It should be pointed out emphatically that an isoperistaltic jejunal interposition (Henley loop) has little or no effect on the early postprandial dumping syndrome and should not be considered. Plicated loops of intestine to recreate a gastric reservoir frequently fail to empty satisfactorily and the incidence of satisfactory results is too low to consider their utilization in surgical treatment of the dumping syndrome.

摘要

通过适当选择适合患者及其所呈现消化性溃疡问题的手术方式,以及在术后早期对饮食给予适当关注,可预防或减轻早期餐后倾倒综合征。当该综合征确实发生时,通常对饮食管理反应良好,且严重程度往往会随时间自行减轻。基于这些原因,早期餐后倾倒综合征很少需要进一步手术。对于经饮食治疗和时间推移仍无改善且出现致残症状并常伴有进行性营养不良的患者,应进行修正手术。外科医生的目标是以延迟胃或胃残余物排空的方式改变重建方式。因此,上段小肠不会接受大量快速注入的高渗团块,从而不会引发导致该综合征的体液物质释放。所有采用的修正手术都有潜在的致溃疡风险,如果迷走神经切断术未作为原手术的一部分,应在修正手术时常规进行。主要接受毕罗Ⅱ式胃切除术的患者,单纯转换为毕罗Ⅰ式重建术通常会有明显改善。当残余胃中等大小(即胃窦切除术后)且胃空肠吻合口直径大于正常空肠时,情况尤其如此。在这种情况下,约80%的患者会有足够改善,以至于无需立即采用更复杂的手术。在所有其他情况下,我们更倾向于将近端与胃残端吻合、远端与40厘米顺蠕动的Roux-en-Y空肠袢吻合的10厘米逆行空肠段。该手术非常成功,即使在解剖结构有利的毕罗Ⅱ式患者中,也可将其作为首选方法。应着重指出,顺蠕动空肠插入术(亨利袢)对早期餐后倾倒综合征几乎没有影响,不应予以考虑。用于重建胃储器的肠袢折叠术往往不能令人满意地排空,满意结果的发生率过低,因此在倾倒综合征的手术治疗中不应考虑使用。

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