Wang X, Lankford J, Agrawal C M
Department of Orthopaedics, University of Texas Health Science Center at San Antonio 78284, USA.
J Appl Biomater. 1994 Winter;5(4):315-23. doi: 10.1002/jab.770050406.
The objective of the present study was to develop a reliable and statistically valid test to measure the fracture toughness of small specimens of bone, and by extension, prosthetic materials, using a compact sandwich specimen. Samples of bone were sandwiched between holders of a different material and using this specimen configuration a new technique was developed to test the fracture toughness of the bone interlayer. The effects of different specimens sizes and holder materials were investigated empirically. Using finite element analysis a correction factor was determined to account for the finite thickness of the interlayer and the analytical solutions governing the test specimen were accordingly modified. Bulk compact tension specimens of bone were tested for comparison. Both wet and dry bone were evaluated and the fracture surface morphology characterized using scanning electron microscopy. The results indicate no statistically significant differences between the fracture toughness values obtained from the compact tension and sandwich specimens. The application of this technique to the testing of interfacial bonding between bone and biomaterials is discussed.
本研究的目的是开发一种可靠且具有统计学有效性的测试方法，以使用紧凑夹层试样来测量小尺寸骨标本以及由此扩展到假体材料的断裂韧性。将骨样本夹在不同材料的夹具之间，并利用这种试样配置开发了一种新技术来测试骨夹层的断裂韧性。通过实验研究了不同试样尺寸和夹具材料的影响。使用有限元分析确定了一个校正因子，以考虑夹层的有限厚度，并相应地修改了控制测试试样的解析解。测试了块状紧凑拉伸骨试样以作比较。对湿骨和干骨都进行了评估，并使用扫描电子显微镜对断裂表面形态进行了表征。结果表明，从紧凑拉伸试样和夹层试样获得的断裂韧性值之间没有统计学上的显著差异。讨论了该技术在测试骨与生物材料之间界面结合方面的应用。
