染色质亚基中组蛋白3巯基的化学计量和可及性

Stoichiometry and accessibility of histone 3 sulfhydryl groups in chromatin subunits.

作者信息

Maher P, Candido E P

出版信息

Can J Biochem. 1977 Apr;55(4):404-7. doi: 10.1139/o77-056.

Abstract

The accessibility of the sulfhydrl groups of histone 3(H3) in chromatin subunit particles has been investigated by reaction with p-hydroxymercuribenzoate. The resuls indicate that the carboxy-terminal regions of H3 are buried in the native particle, and suggest the presence of 2 mol of H3 per chromatin monomer.

摘要

通过与对羟基汞苯甲酸反应，研究了染色质亚基颗粒中组蛋白3（H3）巯基的可及性。结果表明，H3的羧基末端区域埋藏在天然颗粒中，并表明每个染色质单体存在2摩尔H3。