Pryor T L, Martin R L, Roach N
Department of Psychiatry and Behavioral Sciences, University of Kansas School of Medicine-Wichita 67214-3199, USA.
Int J Eat Disord. 1995 Dec;18(4):375-9. doi: 10.1002/1098-108x(199512)18:4<375::aid-eat2260180412>3.0.co;2-s.
We report a case study of an 18-year-old female who presented with symptoms associated with several discrete diagnostic syndromes: obsessive-compulsive disorder, trichotillomania, major depression, and anorexia nervosa. Improvement in each occurred after treatment with the serotonin selective reuptake inhibitor, fluoxetine, suggesting that such syndromes share a common serotonin neurotransmitter disturbance. Furthermore, the combined effects of medication and psychotherapy resulted in improvement in assertiveness, sense of security, self-worth, flexibility, and self-regulation. We discuss the pharmacological and psychotherapeutic implications of possible psychophysiologic similarities among the previously mentioned syndromes.
我们报告了一例18岁女性的病例研究，该患者表现出与几种不同诊断综合征相关的症状：强迫症、拔毛癖、重度抑郁症和神经性厌食症。使用5-羟色胺选择性再摄取抑制剂氟西汀治疗后，每种症状都有所改善，这表明这些综合征存在共同的5-羟色胺神经递质紊乱。此外，药物治疗和心理治疗的联合作用使自信、安全感、自我价值、灵活性和自我调节能力得到改善。我们讨论了上述综合征之间可能存在的心理生理相似性的药理学和心理治疗意义。
