Hopp H, Schaar P, Entezami M, Ebert A, Hundertmark S, Vollert W, Weitzel H
Frauenklinik, Klinikum Benjamin Franklin, FU Berlin.
Geburtshilfe Frauenheilkd. 1995 Dec;55(12):666-70. doi: 10.1055/s-2007-1022310.
The therapeutic approach to ectopic pregnancy (EP) has changed over the last decade. A prerequisite for a differentiated management is an early diagnosis of EP. This can be achieved by transvaginal sonography (TVS). The purpose of this study was to evaluate the accuracy of TVS in the diagnosis of EP. 184 patients with clinically suspected ectopic pregnancy were examined by TVS. In 103 cases suspicion of EP was confirmed, in 81 cases it was ruled out. All cases were evaluated by laparoscopy, D&C, serial HCG determinations or sonographic follow-up in case of an intrauterine pregnancy. Sensitivity of TVS in the diagnosis of EP was 96%, specificity 88%, the positive predictive value was 89%, the negative predictive value was 95%. Four cases with a false negative result at TVS were very early in pregnancy and were subjected to laparoscopy because of persistent high HCG values without demonstration of an intrauterine pregnancy. Five cases of sonographically confirmed ectopic pregnancies were missed by the first laparoscopy. These cases required intervention because of clinical symptoms and had low levels of HCG. TVS has a high diagnostic accuracy in the diagnosis of ectopic pregnancy.
在过去十年中,异位妊娠(EP)的治疗方法发生了变化。进行差异化管理的一个先决条件是早期诊断EP。这可以通过经阴道超声检查(TVS)来实现。本研究的目的是评估TVS诊断EP的准确性。对184例临床怀疑异位妊娠的患者进行了TVS检查。其中103例EP怀疑得到证实,81例被排除。所有病例均通过腹腔镜检查、刮宫术、连续测定HCG或在宫内妊娠情况下进行超声随访进行评估。TVS诊断EP的敏感性为96%,特异性为88%,阳性预测值为89%,阴性预测值为95%。TVS检查结果为假阴性的4例患者处于妊娠极早期,因HCG值持续升高且未发现宫内妊娠而接受了腹腔镜检查。首次腹腔镜检查漏诊了5例经超声确诊的异位妊娠病例。这些病例因临床症状需要干预,且HCG水平较低。TVS在诊断异位妊娠方面具有较高的诊断准确性。