Sharma D C, Mathur R
Department of Biochemistry, S M S Medical College, Jaipur.
Indian J Physiol Pharmacol. 1995 Oct;39(4):403-6.
Twenty-eight strict vegetarians were given 500 mg ascorbic acid twice daily after lunch and dinner for two months. Hemoglobin and certain iron status parameters were measured before and after the treatment. Ascorbate treatment increased mean hemoglobin by 8%, serum iron by 17% and transferrin saturation by 23% and decreased total iron binding capacity by 7%. All these changes were statistically significant. The rise in serum ferritin was 12%. The serum protein or copper level did not indicate their dietary deficiency, while initial serum ascorbate level were low which rose by 60% on therapy. It is concluded that ascorbate supplementation is a better method of improving hematologic and iron status than iron salt administration.
28名严格素食者在午餐和晚餐后每天两次服用500毫克抗坏血酸，持续两个月。在治疗前后测量血红蛋白和某些铁状态参数。抗坏血酸盐治疗使平均血红蛋白增加8%，血清铁增加17%，转铁蛋白饱和度增加23%，总铁结合力降低7%。所有这些变化均具有统计学意义。血清铁蛋白升高12%。血清蛋白或铜水平未显示出饮食缺乏，而初始血清抗坏血酸水平较低，治疗后升高了60%。结论是，补充抗坏血酸比服用铁盐是改善血液学和铁状态的更好方法。
