Sharma A, Mathur R, Dixit V P
Department of Zoology, University of Rajasthan, Jaipur.
Indian J Physiol Pharmacol. 1995 Oct;39(4):407-10.
Myristica seed extr. administration to hypercholesterolemic rabbits reduced serum cholesterol and LDL Cholesterol by 69.1% and 76.3% respectively and also lowered cholesterol/phospholipid ratio by 31.2% and elevated the decreased HDL-ratio significantly. Myristica seed extr. feeding also prevented the accumulation of cholesterol, phospholipids and triglycerides in liver, heart and aorta and dissolved atheromatous plaques of aorta by 70.9-76.5%. Fecal excretion of cholesterol and phospholipid were significantly increased in seed extract fed rabbits.
给高胆固醇血症兔子服用肉豆蔻籽提取物后，血清胆固醇和低密度脂蛋白胆固醇分别降低了69.1%和76.3%，胆固醇/磷脂比率降低了31.2%，同时显著提高了降低的高密度脂蛋白比率。喂食肉豆蔻籽提取物还可防止肝脏、心脏和主动脉中胆固醇、磷脂和甘油三酯的积累，并使主动脉粥样斑块溶解70.9 - 76.5%。喂食种子提取物的兔子粪便中胆固醇和磷脂的排泄量显著增加。
