Richter B, Marangos N, Jeron A, Irscheid S
HNO-Klinik, Universitätsklinik Freiburg.
HNO. 1995 Dec;43(12):728-31.
The occurrence of multilocular malignant tumors in the upper aerodigestive tract in young patients with known marijuana abuse has been described by other authors. A case of a 28-year-old man who was known to abuse alcohol, nicotine and cannabis for some years is presented. He suffered simultaneously from a squamous cell carcinoma of the hypopharynx with bilateral cervical metastases, an adenocarcinoma of the transverse colon and a primary hepatocellular carcinoma. This case is the first reported that shows the occurrence of three separate malignant tumors with different histologies in the aerodigestive tract which could be related to a chronic abuse of cannabis.
其他作者曾描述过已知有大麻滥用史的年轻患者上呼吸消化道出现多房性恶性肿瘤的情况。本文介绍了一名28岁男性病例，该男子已知有多年酗酒、吸烟和吸食大麻史。他同时患有下咽鳞状细胞癌伴双侧颈部转移、横结肠腺癌和原发性肝细胞癌。该病例是首例报告显示上呼吸消化道出现三种不同组织学类型的独立恶性肿瘤，且可能与长期滥用大麻有关。
