Apgar G A, Kornegay E T, Lindemann M D, Notter D R
Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg 24061-0306, USA.
J Anim Sci. 1995 Sep;73(9):2640-6. doi: 10.2527/1995.7392640x.
Two 5-wk trials using 176 weanling pigs (average initial weight of 8.3 kg and age of 31 d) were conducted to examine the effect of feeding varying levels of dietary Cu from copper sulfate (CuSO4) or a copper lysine complex (CuLys) on performance, mineral stores, serum copper, and serum mitogenic activity. Dietary treatments were 0 (15 mg/kg of Cu in basal diet), 100, 150, or 200 mg/kg of supplemental Cu from CuSO4 or CuLys. Average daily gain and ADFI increased linearly (P < .01) with increasing dietary levels of Cu during wk 1 to 2, 3 to 5, and 1 to 5, with no difference (P > .10) between the Cu sources. Overall gain:feed ratios were not consistently affected by Cu source. Dietary Cu linearly increased liver, kidney (P < .001), and brain (P < .05) concentrations of Cu. In the liver, the linear response to supplemental Cu differed between Cu sources (P < .001); pigs fed 200 mg/kg of Cu from CuLys had the highest concentration of Cu. Serum Cu concentrations increased linearly during wk 1 to 2 (P < .01), 3 to 5, and 1 to 5 (P < .001), with no difference (P > .10) between sources. Serum mitogenic activity increased linearly during wk 1 to 2 and 1 to 5 (P < .05). Growth performance was linearly improved as the dietary level of Cu increased from 15 to 200 mg/kg, with similar responses for both Cu sources. Serum and tissue concentrations of Cu were generally equally affected by the two Cu sources, except liver Cu concentration, which was onefold higher for pigs fed 200 mg/kg of Cu as CuLys.
进行了两项为期5周的试验，使用176头断奶仔猪（平均初始体重8.3千克，年龄31天），以研究从硫酸铜（CuSO4）或赖氨酸铜络合物（CuLys）中添加不同水平的日粮铜对生长性能、矿物质储备、血清铜和血清促有丝分裂活性的影响。日粮处理包括0（基础日粮中含15毫克/千克铜）、100、150或200毫克/千克来自CuSO4或CuLys的补充铜。在第1至2周、第3至5周和第1至5周期间，平均日增重和平均日采食量随日粮铜水平的增加呈线性增加（P <.01），两种铜源之间无差异（P>.10）。总体增重：饲料比不受铜源的一致影响。日粮铜使肝脏、肾脏（P <.001）和大脑（P <.05）中的铜浓度线性增加。在肝脏中，两种铜源对补充铜的线性反应不同（P <.001）；饲喂来自CuLys的200毫克/千克铜的猪铜浓度最高。血清铜浓度在第1至2周（P <.01）、第3至5周和第1至5周（P <.001）呈线性增加，两种来源之间无差异（P>.10）。血清促有丝分裂活性在第1至2周和第1至5周呈线性增加（P <.05）。随着日粮铜水平从15毫克/千克增加到200毫克/千克，生长性能呈线性改善，两种铜源的反应相似。除肝脏铜浓度外，两种铜源对血清和组织铜浓度的影响通常相同，饲喂200毫克/千克作为CuLys的铜的猪肝脏铜浓度高一倍。
