Niv Y, Henkin Y
Department of Gastroenterology, Soroka Medical Center, Beer-Sheva, Israel.
J Clin Gastroenterol. 1995 Dec;21(4):295-7. doi: 10.1097/00004836-199512000-00009.
We describe two elderly men with preexisting coronary heart disease (CHD) and prostatic carcinoma who presented with intractable anemia due to radiation-induced rectal telangiectases and bleeding. Remission of the bleeding was achieved in both patients by treatment with an estrogen-progestin preparation. However, aggravation of the CHD occurred in both patients. We believe that estrogen-progestin preparations have a potential in the treatment of men with radiation-induced rectal telangiectases, but additional studies are needed to evaluate their long-term effects and optimal dose.