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Urolume尿道支架治疗复发性尿道狭窄的长期效果

Long-term results of urolume urethral stent for recurrent urethral strictures.

作者信息

Milroy E, Allen A

机构信息

Department of Urology, St. Peter's Hospitals, London, United Kingdom.

出版信息

J Urol. 1996 Mar;155(3):904-8.

PMID:8583603
Abstract

PURPOSE

We present the long-term results of the first 50 patients treated with a new urethral stent (UroLume) developed in 1985 for recurrent bulbomembranous urethral strictures.

MATERIALS AND METHODS

All stents were inserted with the patient under general anesthesia using a standard endoscopic delivery system. Of the patients 27 were followed for 5 years or longer, 5 for 4 years and 18 for shorter periods due to death, illness or other factors.

RESULTS

Mean (plus or minus standard deviation) maximum flow rate at last following was 19.7 ml. per second (+/- 6.9), and 93% of the patients were satisfied with the stent. In 8 patients (16%) narrowing developed within the lumen of the stent and in the remaining 84% the stent achieved its purpose of maintaining a good urethral lumen. In 9 patients stricture recurred outside the stent because of inaccurate positioning. All of these complications were satisfactorily treated by an additional overlapping stent. Failures occurred particularly in patients with a long stricture history and extensive periurethral fibrosis.

CONCLUSIONS

These results indicate that at 4 to 6 years promising early results with the UroLume stent for urethral strictures are maintained with a low late failure rate. This device is not suitable for all strictures and cases with extensive periurethral fibrosis should be avoided but it remains a useful and successful treatment option for many recurrent bulbomembranous urethral strictures.

摘要

目的

我们展示了1985年研发的一种新型尿道支架(UroLume)治疗首批50例复发性球膜部尿道狭窄患者的长期结果。

材料与方法

所有支架均在全身麻醉下使用标准内镜输送系统为患者置入。27例患者随访5年或更长时间,5例随访4年,18例因死亡、疾病或其他因素随访时间较短。

结果

末次随访时平均(±标准差)最大尿流率为19.7毫升/秒(±6.9),93%的患者对支架满意。8例患者(16%)支架腔内出现狭窄,其余84%的支架达到了维持良好尿道腔的目的。9例患者因定位不准确在支架外复发狭窄。所有这些并发症通过额外置入重叠支架均得到满意治疗。失败尤其发生在狭窄病史长和尿道周围广泛纤维化的患者中。

结论

这些结果表明,4至6年时,UroLume尿道支架早期的良好结果得以维持,晚期失败率较低。该装置并不适用于所有狭窄,应避免用于尿道周围广泛纤维化的病例,但对于许多复发性球膜部尿道狭窄,它仍是一种有用且成功的治疗选择。

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