Milroy E, Allen A
Department of Urology, St. Peter's Hospitals, London, United Kingdom.
J Urol. 1996 Mar;155(3):904-8.
We present the long-term results of the first 50 patients treated with a new urethral stent (UroLume) developed in 1985 for recurrent bulbomembranous urethral strictures.
All stents were inserted with the patient under general anesthesia using a standard endoscopic delivery system. Of the patients 27 were followed for 5 years or longer, 5 for 4 years and 18 for shorter periods due to death, illness or other factors.
Mean (plus or minus standard deviation) maximum flow rate at last following was 19.7 ml. per second (+/- 6.9), and 93% of the patients were satisfied with the stent. In 8 patients (16%) narrowing developed within the lumen of the stent and in the remaining 84% the stent achieved its purpose of maintaining a good urethral lumen. In 9 patients stricture recurred outside the stent because of inaccurate positioning. All of these complications were satisfactorily treated by an additional overlapping stent. Failures occurred particularly in patients with a long stricture history and extensive periurethral fibrosis.
These results indicate that at 4 to 6 years promising early results with the UroLume stent for urethral strictures are maintained with a low late failure rate. This device is not suitable for all strictures and cases with extensive periurethral fibrosis should be avoided but it remains a useful and successful treatment option for many recurrent bulbomembranous urethral strictures.
我们展示了1985年研发的一种新型尿道支架(UroLume)治疗首批50例复发性球膜部尿道狭窄患者的长期结果。
所有支架均在全身麻醉下使用标准内镜输送系统为患者置入。27例患者随访5年或更长时间,5例随访4年,18例因死亡、疾病或其他因素随访时间较短。
末次随访时平均(±标准差)最大尿流率为19.7毫升/秒(±6.9),93%的患者对支架满意。8例患者(16%)支架腔内出现狭窄,其余84%的支架达到了维持良好尿道腔的目的。9例患者因定位不准确在支架外复发狭窄。所有这些并发症通过额外置入重叠支架均得到满意治疗。失败尤其发生在狭窄病史长和尿道周围广泛纤维化的患者中。
这些结果表明,4至6年时,UroLume尿道支架早期的良好结果得以维持,晚期失败率较低。该装置并不适用于所有狭窄,应避免用于尿道周围广泛纤维化的病例,但对于许多复发性球膜部尿道狭窄,它仍是一种有用且成功的治疗选择。